Capable of monitoring decreasing temperatures, these indicators undergo an irreversible color change, clearly signaling a temperature drop below the specified threshold. Particularly advantageous for pharmaceutical and vaccine temperature control, these indicators boast economic efficiency and compact design. Available for temperature monitoring at 2°C and 0°C, they exhibit a reaction speed ranging from 30 to 90 minutes of exposure, ensuring accuracy with a margin of +/- 1°C. With a shelf life of two years from the production date, these indicators offer a reliable solution for precise and timely temperature monitoring.